- Pyruvate → acetyl-CoA produces 1 NADH, 1 CO2.
- The TCA cycle produces 3 NADH, 1 FADH2, 2 CO2, 1 GTP per acetyl-CoA = 10 ATP/acetyl-CoA (2× everything per glucose).
- TCA cycle reactions occur in the mitochondria.
- α-ketoglutarate dehydrogenase complex requires the same cofactors as the pyruvate dehydrogenase complex (B1, B2, B3, B5, lipoic acid).
- Citrate Is Krebs’ Starting Substrate For Making Oxaloacetate.