Vitamin E

  • Includes tocopherol, tocotrienol.
  • Function
    • Antioxidant (protects RBCs and membranes from free radical damage).
  • Deficiency
    • No protection against oxidative injury (especially in long axons with large membrane surface area and erythrocytes with high oxygen exposure)
    • Hemolytic anemia, acanthocytosis
    • Muscle weakness, posterior column and spinocerebellar tract demyelination (loss of proprioception and vibratory sense)
    • Neurologic presentation may appear similar to vitamin B12 deficiency, but without megaloblastic anemia, hypersegmented neutrophils, or ↑ serum methylmalonic acid levels.
    • Risk of enterocolitis in infants.
    • High-dose supplementation may alter metabolism of vitamin K → enhanced anticoagulant effects of warfarin → hemorrhagic stroke in adults

Filipino MD

An independent organization catered to bringing enriching opportunities to doctors, researchers and medical institutions.


Like Us On Facebook

Facebook Pagelike Widget

You cannot copy the contents of this page.