HLA Subtypes Associated with Diseases

HLA SUBTYPE DISEASE MNEMONIC
A3 Hemochromatosis  
B8 Addison disease, myasthenia gravis, Graves Disease Don’t Be late(8), Dr. Addison, or else you’ll send my patient to the grave.
B27 Psoriatic arthritis, Ankylosing spondylitis, IBD-associated arthritis, Reactive arthritis PAIR. Also known as seronegative arthropathies.
B51 Behcet syndrome  
DQ2/DQ8 Celiac disease I ate (8) too (2) much gluten at Dairy Queen.
DR2 Multiple sclerosis, hay fever, SLE, Goodpasture syndrome Multiple hay pastures have dirt.
DR3 Diabetes mellitus type 1, SLE, Graves disease, Hashimoto thyroiditis, Addison disease 2-3, S-L-E
DR4 Rheumatoid arthritis, diabetes mellitus type 1, Addison disease There are 4 walls in a “rheum” (room).

Dr. Addison Bate (B8), 34 y/o (DR3, DR4)

DR5 Hashimoto thyroiditis Hashimoto is an odd doctor (DR3, DR5).

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