CYTOKINE | AGENT | CLINICAL USES |
Bone marrow stimulation | ||
Erythropoietin | Epoetin alfa (EPO analog) | Anemias (especially in renal failure) |
Colony stimulating factors | Filgrastim (G-CSF), Sargramostim (GM-CSF) | Leukopenia; recovery of granulocyte and monocyte counts |
Thrombopoietin | Romiplostim (TPO analog), eltrombopag (TPO receptor agonist) | Autoimmune thrombocytopenia |
Immunotherapy | ||
Interleukin-2 | Aldesleukin | Renal cell carcinoma, metastatic melanoma |
Interferon | IFN-α | Chronic hepatitis C (not preferred) and B, renal cell carcinoma |
IFN-β | Multiple sclerosis | |
IFN-γ | Chronic granulomatous disease |