Recombinant Cytokines and Clinical Uses

CYTOKINE AGENT CLINICAL USES
Bone marrow stimulation    
Erythropoietin Epoetin alfa (EPO analog) Anemias (especially in renal failure)
Colony stimulating factors Filgrastim (G-CSF), Sargramostim (GM-CSF) Leukopenia; recovery of granulocyte and monocyte counts
Thrombopoietin Romiplostim (TPO analog), eltrombopag (TPO receptor agonist) Autoimmune thrombocytopenia
Immunotherapy    
Interleukin-2 Aldesleukin Renal cell carcinoma, metastatic melanoma
Interferon IFN-α Chronic hepatitis C (not preferred) and B, renal cell carcinoma
  IFN-β Multiple sclerosis
  IFN-γ Chronic granulomatous disease

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